Week of Feb. 5, 2024

This week we highlight the acquisition of a contract manufacturing organization to meet the high demand for GLP-1s, the funding of Australian medtech startups, and a shift in pharma from large deals to smaller acquisitions. We also examine the investment into the psychedelic medicine industry. Additionally, we look at the introduction of an artificial intelligence-powered virtual therapy.

Each week we highlight five things affecting the life sciences industry. Here’s the latest.

According to The Washington Post, Novo Nordisk is addressing the high demand for its weight-loss drug Wegovy by acquiring additional manufacturing capacity. Novo Holdings, the Danish drugmaker’s controlling shareholder, has purchased the New Jersey-based Catalent in a deal valued at $16.5 billion. Subsequently, Novo Nordisk will acquire three manufacturing sites from Novo Holdings for $11 billion, a move to enhance production capabilities for Wegovy, which has seen surging patient demand.

Australia’s Medical Research Future Fund has invested $3.25 million in non-dilutive funding across four Australian medtech startups, all integrating AI and machine learning into their health care solutions, reports SmartCompany. The recipients, chosen through the ANDHealth+ digital health commercialization program, include Macuject, Baymatob, Neurotologix, and WeGuide. This investment aims to help these startups achieve key clinical and commercial milestones and expand their global market presence. Baymatob’s AI-supported wearable, Oli, has already received U.S. Food and Drug Administration breakthrough device designation, highlighting its potential in maternal care, while Macuject focuses on early detection of macular degeneration. The funding reflects the growing importance of AI and machine learning in health care innovation, supporting Australian digital health businesses in solving real health problems and contributing to the country’s economic growth through health care efficiencies and exports.

According to Mergers & Acquisitions, pharmaceutical companies are increasingly targeting smaller, innovative biotech firms for acquisitions, moving away from the large-scale megadeals that previously characterized the sector. This strategic shift aims to fill gaps in their product pipelines, often focusing on specific drugs in advanced clinical trials that can either open new disease areas or strengthen existing ones. The trend reflects a cautious approach to avoid regulatory pushback associated with larger acquisitions. Additionally, some pharmaceutical companies are refocusing on prescription medicines and divesting businesses considered peripheral, indicating a significant realignment in their operational strategies. This change underscores the evolving dynamics of the pharmaceutical industry, where targeted, strategic acquisitions are becoming the norm.

AP News reports a significant influx of investment into the psychedelic medicine industry, with numerous startups racing to commercialize mind-expanding drugs for mental health conditions. Despite federal illegality, companies are patenting key ingredients from substances like magic mushrooms and ayahuasca, historically used by indigenous cultures. Wall Street’s interest in psychedelics, however, has raised concerns among advocates who envisioned making these drugs widely available for mental health and personal growth. The industry faces challenges in transforming these substances into profitable medicines, with companies focusing on rigorous clinical studies to gain FDA approval and insurance coverage. This trend indicates a shift in the pharmaceutical landscape, where psychedelics are being reimagined as potential mainstream treatments for mental health disorders.

Fierce Biotech reports on Cedars-Sinai’s development of an innovative AI-powered therapy app, Xaia, designed for use with Apple’s new Vision Pro virtual reality headset. Xaia, a virtual therapist, offers immersive therapy sessions in calming environments, using cognitive behavioral therapy and other techniques. The app, now available on the Vision Pro headset, features a 3D avatar in settings like beaches or meadows, enhancing the therapy experience. This technology represents a significant advancement in virtual care, offering an engaging and deeply personal form of mental health support. The effectiveness of Xaia has been validated in a study, with patients finding the virtual avatar approachable and empathetic, although some still prefer human therapists.

For more insights in life sciences, check out RSM’s industry outlook.

Source link: https://realeconomy.rsmus.com/5-things-to-know-in-life-sciences-week-of-feb-5-2024/ by Justin Culbertson at realeconomy.rsmus.com